Compounds for the treatment and prophylaxis of Respiratory Syncytial Virus disease

US8871756B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Li Chen · Shanghai, CN
• Lichun Feng · Shanghai, CN
• Song Feng · Shanghai, CN
• Lu Gao · Shanghai, CN
• Tao Guo
• Mengwei Huang · Shanghai, CN
• Chungen Liang · Shanghai, CN
• Yongfu Liu · Shanghai, CN
• Lisha Wang · Basel, CH
• Jason Christopher Wong · Cambridge, US
• Jim Zhen Wu · Shanghai, CN
• Xihan Wu · Shanghai, CN
• Hongying Yun · Shanghai, CN
• Xiufang Zheng · Shanghai, CN

Key dates

• Filing date: Jul 30, 2012
• Grant date: Oct 28, 2014
• Expiry date: Dec 27, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/107
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound of formula (I)as well as pharmaceutically acceptable salt thereof, wherein R1 to R10, A, Q, X and Y are as defined in the specification and claims, and their use as a pharmaceutical for the treatment or prophylaxis of respiratory syncytial virus disease.