Antiviral phosphonate analogs

US8871785B2 · kind B2 · utility

Assignee

• Gilead Sciences, Inc. · US

Inventors

• Constantine G. Boojamra · San Francisco, US
• Carina E. Cannizzaro · San Mateo, US
• James M. Chen · Bedminster, US
• Xiaowu Chen · Hillsborough, US
• Aesop Cho · Mountain View, US
• Lee S. Chong · Newark, US
• Maria Fardis · Redwood City, US
• Haolun Jin · Foster City, US
• Ralph F. Hirschmann · La Cañada Flintridge, US
• Alan X. Huang · San Mateo, US
• Choung U. Kim · Redwood City, US
• Thorsten A. Kirschberg · Mountain View, US
• Christopher P. Lee · San Francisco, US
• William A. Lee · Palo Alto, US
• Richard L. Mackman · Millbrae, US
• David Y. Markevitch · Los Angeles, US
• David A. Oare · Belmont, US
• Vidya K. Prasad · Munich, DE
• Hyung-Jung Pyun · Fremont, US
• Adrian S. Ray · Redwood City, US
• Rosemarie O'Shea · Redwood City, US
• Sundaramoorthi Swaninathan · Burlingame, US
• William J. Watkins · Saratoga, US
• Jennifer R. Zhang · Union City, US

Key dates

• Filing date: Mar 21, 2013
• Grant date: Oct 28, 2014
• Expiry date: Mar 21, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.