Patent · US Active

Antibodies to human programmed death receptor PD-1

US8900587B2 · kind B2 · utility

128Cited by
16References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 19, 2012
Grant dateDec 2, 2014
Priority date—
Expiry dateFeb 27, 2033

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/52
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Antibodies which block binding of hPD-1 to hPD-L1 or hPD-L2 and their variable region sequences are disclosed. A method of increasing the activity (or reducing downmodulation) of an immune cell through the PD-1 pathway is also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.