Derivatives of APF and methods of use

US8912146B2 · kind B2 · utility

Assignees

• UNIVERSITY OF MARYLAND, BALTIMORE · US
• The United States of America, as represented by the Department of Health and Human Services · US
• DEPARTMENT OF VETERANS AFFAIRS · US

Inventors

• Christopher J. Michejda · North Potomac, US
• Susan K. Keay · Ellicott City, US
• Zoltan Szekely · Frederick, US
• Piotr Kaczmarek · Mississauga, CA

Key dates

• Filing date: Aug 18, 2009
• Grant date: Dec 16, 2014
• Expiry date: Sep 27, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Derivatives of bladder epithelial antiproliferative factor and methods of using them are disclosed. In specific embodiments, the glycopeptide compositions are useful for the treatment and/or prevention of medical conditions, including cancer. In other embodiments, there are compositions and methods related to treatment of bladder conditions. In particular embodiments, the glycopeptide comprises D-pipecolic acid or L-pipecolic acid.