Use of Chk2 kinase inhibitors for cancer treatment

US8912214B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Secretary, Department of Health and Human Services · US

Inventors

• Yves Pommier · Bethesda, US
• Robert H. Shoemaker · Royal Oak, US
• Dominic Scudiero · Frederick, US
• Michael Currens · Frederick, US
• John H. Cardellina, II · Fort Detrick, US
• Andrew Jobson · Coventry, GB

Key dates

• Filing date: Jul 27, 2006
• Grant date: Dec 16, 2014
• Expiry date: Jun 8, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are Chk2-inhibitor compounds and derivatives thereof, and methods of treating or preventing disease and disease symptoms using the compounds and compositions thereof.