Heteroaryl pyridone and aza-pyridone compounds
US8921353B2 · kind B2 · utility
10Cited by
9References
22Claims
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Key dates
| Filing date | Mar 13, 2014 |
| Grant date | Dec 30, 2014 |
| Priority date | — |
| Expiry date | Mar 13, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1804
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Heteroaryl pyridone and aza-pyridone compounds of Formula I are provided, where one or two of X1, X2, and X3 are N, and including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.