Integration of very short electric pulses for minimally to noninvasive electroporation
US8926606B2 · kind B2 · utility
114Cited by
129References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 2010 |
| Grant date | Jan 6, 2015 |
| Priority date | — |
| Expiry date | Apr 10, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/0424
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) or supra-poration to cause cell death in treated tumors. In embodiments, the methods comprise the integration of ultra-short electric pulses, both temporally and spatially, to achieve the desired modality of cell death.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.