Method for expanding hematopoietic stem cells
US8927281B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 29, 2009 |
| Grant date | Jan 6, 2015 |
| Priority date | — |
| Expiry date | Aug 12, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds and compositions for expanding the number of CD34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (HSCs) and its use in autologous or allogeneic transplantation for the treatment of patients with inherited immunodeficient and autoimmune diseases and diverse hematopoietic disorders to reconstitute the hematopoietic cell lineages and immune system defense.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.