Macrocyclic compounds as antiviral agents
US8927569B2 · kind B2 · utility
0Cited by
8References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 17, 2008 |
| Grant date | Jan 6, 2015 |
| Priority date | — |
| Expiry date | Apr 17, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0808
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A class of macrocyclic compounds of formula (I), wherein R1, R3, R4, Ra, Rb, A, Z, Y, X, M, W, n and m are defined herein, that are useful as inhibitors of viral proteases, particularly the hepatitis C virus (HCV) NS3 protease, are provided. Also provided are processes 5 for the synthesis and use of such macrocyclic compounds for treating or preventing HCV infection. Formula (I):
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.