Methods and compositions for inhibiting the nuclear factor κB pathway

US8945632B2 · kind B2 · utility

Assignees

• Ben Gurion University of the Negev R&D Authority · IL
• MOR RESEARCH APPLICATIONS LTD. · IL

Inventors

• Avi Golan · Nes Ziona, IL
• Jacob GOPAS · Beer Sheva, IL
• Janet Ozer · Ashdod, IL
• Nadav Eisner · Gdera, IL
• Adelbert Bacher · Garching bei München, DE
• Wolfgang Eisenreich · Garching bei München, DE
• Elena Ostrozhenkova · Jena, DE
• Hila Winer · Raanana, IL

Key dates

• Filing date: Jul 19, 2011
• Grant date: Feb 3, 2015
• Expiry date: Jul 19, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The current invention provides therapeutic methods which include inhibition of nuclear factor κb pathway in a cell based on the discovery of an active fraction of a plant extract termed NUP or a composition which includes NUP. NUP is used in treating and managing different diseases such as cancer, inflammation, and virus infections.