Patent · US Active

DNA polymerases with improved activity

US8945882B2 · kind B2 · utility

7Cited by

2References

21Claims

0Family size

Assignee

Roche Molecular Systems, Inc. · US

Inventors

Keith Bauer · Los Altos, US
Thomas W. Myers · Dublin, US
Shawn Suko · El Sobrante, US

Key dates

Filing date	Dec 5, 2012
Grant date	Feb 3, 2015
Priority date	—
Expiry date	Jan 3, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y207/07007
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.