Piperidine/piperazine derivatives

US8946228B2 · kind B2 · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Jean-Pierre Andre Marc Bongartz · Turnhout, BE
• Joannes Theodorus Maria Linders · Eindhoven, NL
• Lieven Meerpoel · Beerse, BE
• Guy Rosalia Eugeen Van Lommen · Berlaar, BE
• Erwin Coesemans · Nijlen, BE
• Mirielle Braeken · Vlimmeren, BE
• Christophe Francis Robert Nestor Buyck · Temse, BE
• Monique Berwaer · Montigny-le-Tilleul, BE
• Katharina Antonia Germania J. M. De Waepenaert · Vosselaar, BE
• Peter Walter Maria Roevens · Malle, BE
• Petr Vladimirivich Davidenko · Moscow, RU

Key dates

• Filing date: Jun 6, 2008
• Grant date: Feb 3, 2015
• Expiry date: Jun 6, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a DGAT inhibitor of formula (I),including any stereochemically isomeric form thereof, a N-oxide thereof, a pharmaceutically acceptable salt thereof or a solvate thereof, and methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use as a medicine, as a DGAT inhibitor, of said compounds.