Selective reduction of allelic variants
US8957040B2 · kind B2 · utility
39Cited by
11References
16Claims
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Key dates
| Filing date | Feb 8, 2011 |
| Grant date | Feb 17, 2015 |
| Priority date | — |
| Expiry date | Feb 8, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/35
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are antisense compounds and methods for selectively of reducing expression of an allelic variant of a gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate diseases, including neurodegenerative, such as Huntington's Disease (HD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.