Patent · US Active

Processes for preparing JAK inhibitors and related intermediate compounds

US8993582B2 · kind B2 · utility

56Cited by
8References
1Claims
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Key dates

Filing dateFeb 7, 2013
Grant dateMar 31, 2015
Priority date
Expiry dateFeb 7, 2033

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.

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