Compositions and methods for enhancing immune responses to vaccines

US8999345B2 · kind B2 · utility

Assignee

• Vical Incorporated · US

Inventors

• Jukka Hartikka · Lemon Grove, US
• Sean M. Sullivan · Boulder, US
• Joel D. Enas · Fallbrook, US
• Alain Rolland · Palaiseau, FR

Key dates

• Filing date: Aug 3, 2012
• Grant date: Apr 7, 2015
• Expiry date: Aug 3, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D211/44
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure provides adjuvants, immunogenic compositions, and methods useful for vaccination and immune response. In particular, the disclosure provides a class of adjuvants comprising cationic lipid:co-lipid mixtures and methods for delivering formulated compositions.