Compounds and methods for improving cellular uptake of oligomeric compounds
US8999951B2 · kind B2 · utility
0Cited by
2References
19Claims
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Key dates
| Filing date | Oct 23, 2012 |
| Grant date | Apr 7, 2015 |
| Priority date | — |
| Expiry date | Oct 23, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides method of optimizing the efficacy and potency of antisense drugs. In certain embodiments, the invention provides assays useful for determining favorable oligonucleotide characteristics and excipients for improved cellular uptake.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.