Optoelectronic detection system

US9005989B2 · kind B2 · utility

Assignee

• Massachusetts Institute of Technology · US

Inventors

• James D. Harper · Hazel Green, US
• Richard H. Mathews · Chelmsford, US
• Bernadette Johnson · Hollis, US
• Martha S. Petrovick · Barre, US
• Ann Rundell · West Lafayette, US
• Frances E. Nargi · Littleton, US
• Timothy Stephens · Lexington, US
• Linda Marie Mendenhall · Acton, US
• Mark A. Hollis · Concord, US
• Albert M. Young · Fishkill, US
• Todd H. Rider · Littleton, US
• Eric Schwoebel · Woburn, US
• Trina Rae Vian · Westford, US

Key dates

• Filing date: Mar 3, 2011
• Grant date: Apr 14, 2015
• Expiry date: May 23, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S436/805
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention relates to optoelectronic systems for detecting one or more target particles. The system includes a reaction chamber, a specimen collector, an optical detector, and a reservoir containing cells, each of the cells having receptors which are present on the surface of each cell and are specific for the target particle to be detected, where binding of the target particle to the receptors directly or indirectly activates a reporter molecule, thereby producing a measurable optical signal.