Patent · US Active

Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof

US9018243B2 · kind B2 · utility

8Cited by

71References

21Claims

0Family size

Assignee

CELGENE CORPORATION · US

Inventors

George W. Muller · Northbrook, US
Peter Schafer · Ottersheim, DE
Hon-Wah Man · Princeton, US
Chuansheng Ge · Montgomery, US
Jean Xu · Hackettstown, US

Key dates

Filing date	Dec 10, 2013
Grant date	Apr 28, 2015
Priority date	—
Expiry date	Dec 10, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/07
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.