Thiopyrimidine-based compounds and uses thereof
US9040549B2 · kind B2 · utility
5Cited by
1References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 11, 2013 |
| Grant date | May 26, 2015 |
| Priority date | — |
| Expiry date | Apr 11, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/506
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to thiopyrimidine-based compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2 or JAK3 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases and vascular diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.