Diphosphonate compound and a method for preparing the same and an application of the same
US9045506B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Aug 24, 2011 |
| Grant date | Jun 2, 2015 |
| Priority date | — |
| Expiry date | Aug 24, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/5475
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure relates to a new diphosphonate compound, and the method to prepare the above new diphosphonate compound. The new diphosphonate compound exhibits an activity in inhibiting osteoclast equivalent to alendronate sodium, and a higher activity in affecting the proliferation of osteoplast than the positive control compounds, but the positive control exhibits a weaker effect on osteoblast proliferation. In experimental examples, an administration schedule for the diphosphonate compound is provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.