Linear donor constructs for targeted integration
US9045763B2 · kind B2 · utility
50Cited by
20References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 16, 2011 |
| Grant date | Jun 2, 2015 |
| Priority date | — |
| Expiry date | Oct 16, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/8213
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are linear donor molecules comprising homology arms of 50-750 base pairs (e.g., 50-100 base pairs) flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for integration of an exogenous sequence into a specified region of interest in the genome of a cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.