1,4 thiazepines/sulfones as BACE1 and/or BACE2 inhibitors
US9067924B2 · kind B2 · utility
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23Claims
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Key dates
| Filing date | Feb 27, 2012 |
| Grant date | Jun 30, 2015 |
| Priority date | — |
| Expiry date | Jul 5, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to 1,4 Thiazepines/Sulfones of formula Ihaving BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.