Substituted nucleosides, nucleotides and analogs thereof

US9073960B2 · kind B2 · utility

Assignee

• ALIOS BIOPHARMA, INC. · US

Inventors

• Leonid Beigelman · San Mateo, US
• Guangyi Wang · Carlsbad, US
• David Bernard Smith · San Mateo, US
• Jerome Deval · Pacifica, US
• Marija Prhavc · Encinitas, US

Key dates

• Filing date: Dec 20, 2012
• Grant date: Jul 7, 2015
• Expiry date: May 19, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y207/07048
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are nucleosides, nucleotides and analogs thereof, pharmaceutical compositions that include one or more of nucleosides, nucleotides and analogs thereof, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a disease and/or a condition, including an infection from a paramyxovirus and/or an orthomyxovirus, with a nucleoside, a nucleotide and an analog thereof.