Patent · US Active

Methods for the preparation of diasteromerically pure phosphoramidate prodrugs

US9090642B2 · kind B2 · utility

87Cited by
34References
34Claims
0Family size

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Key dates

Filing dateJul 19, 2011
Grant dateJul 28, 2015
Priority date
Expiry dateJan 21, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/20
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided are methods and intermediates for preparing diastereomerically pure phosphoramidate prodrugs of nucleosides of Formulas Ia and Ib:The compounds of Formula Ia and Ib are useful for the treatment Hepatitis C infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.