Substituted pyrrolo[3,2-c]pyridines as TrkA kinase inhibitors
US9102673B2 · kind B2 · utility
1Cited by
4References
14Claims
0Family size
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Key dates
| Filing date | Jul 6, 2012 |
| Grant date | Aug 11, 2015 |
| Priority date | — |
| Expiry date | Jul 26, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds of formula I and Ia: which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.