Quinoline derivatives as bromodomain inhibitors
US9108953B2 · kind B2 · utility
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18Claims
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Key dates
| Filing date | Nov 21, 2014 |
| Grant date | Aug 18, 2015 |
| Priority date | — |
| Expiry date | Nov 21, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D451/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula Iwherein R1, R2, R3, R4, R7, W, X, and Z are as described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.