Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione

US9139556B2 · kind B2 · utility

Assignee

• CELGENE CORPORATION · US

Inventors

• Markian S. Jaworsky · Hopewell, US
• Roger Shen-Chu Chen · Edison, US
• George W. Muller · Northbrook, US
• Manohar T. Saindane · Monmouth Junction, US
• Louise M. Cameron · Plainsboro, US

Key dates

• Filing date: Sep 22, 2011
• Grant date: Sep 22, 2015
• Expiry date: Sep 22, 2031

Classification

• Technology area (CPC —): General

Abstract

Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of making the polymorphic forms and methods of their use are also disclosed.