Fluorine-18 and carbon-11 labeled radioligands for positron emission tomography (PET) imaging for LRRK2
US9139566B2 · kind B2 · utility
6Cited by
1References
12Claims
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Key dates
| Filing date | Nov 28, 2012 |
| Grant date | Sep 22, 2015 |
| Priority date | — |
| Expiry date | Nov 28, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/48
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for positron emission tomography (PET) imaging of LRRK2 in tissue of a subject, the method comprising: administering a compound of formula I, formula II or formula III, or a pharmaceutically acceptable salt thereof to the subject, wherein the compound includes at least one C11 or F18 label thereon; allowing the compound to penetrate into the tissue of the subject; and collecting a PET image of the CNS or brain tissue of the subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.