Heterocyclic carboxamides as modulators of kinase activity

US9139568B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Bayard R. Huck · Sudbury, US
• Xiaoling Chen · Sharon, US
• Yufang Xiao · Lexington, US
• Ruoxi Lan · Waltham, US
• Lizbeth Celeste De Selm · Melrose, US
• Constantin Neagu · Belmont, US
• Justin Potnick · Acton, US
• Srinivasa Karra · Pembroke, US
• Theresa L. Johnson · Salem, US

Key dates

• Filing date: Dec 17, 2012
• Grant date: Sep 22, 2015
• Expiry date: Dec 17, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides novel heterocyclic carboxamide compounds according to Formula (I),their manufacture, and use for the treatment of hyperproliferative diseases, such as cancer.