Antiviral phosphonate analogs

US9139604B2 · kind B2 · utility

Assignee

• Gilead Sciences, Inc. · US

Inventors

• Constantine G. Boojamra · San Francisco, US
• Carina E. Cannizzaro · San Mateo, US
• James M. Chen · Bedminster, US
• Xiaowu Chen · Hillsborough, US
• Aesop Cho · Mountain View, US
• Lee S. Chong · Newark, US
• Maria Fardis · Redwood City, US
• Haolun Jin · Foster City, US
• Ralph F. Hirschmann · La Cañada Flintridge, US
• Alan X. Huang · San Mateo, US
• Choung U. Kim · Redwood City, US
• Thorsten A. Kirschberg · Mountain View, US
• Christopher P. Lee · San Francisco, US
• William A. Lee · Palo Alto, US
• Richard L. Mackman · Millbrae, US
• David Y. Markevitch · Los Angeles, US
• David A. Oare · Belmont, US
• Vidya K. Prasad · Munich, DE
• Hyung-Jung Pyun · Fremont, US
• Adrian S. Ray · Redwood City, US
• Rosemarie O'Shea · Redwood City, US
• Sundaramoorthi Swaminathan · Burlingame, US
• William J. Watkins · Saratoga, US
• Jennifer R. Zhang · Union City, US

Key dates

• Filing date: Jun 19, 2014
• Grant date: Sep 22, 2015
• Expiry date: Jun 19, 2034

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.