Methods and compositions in particle-based detection of target molecules using linking molecules
US9150910B2 · kind B2 · utility
7Cited by
31References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 4, 2009 |
| Grant date | Oct 6, 2015 |
| Priority date | — |
| Expiry date | Nov 24, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6834
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions which can be used to increase the strength and/or probability of forming a binding complex comprising a target molecule and a substrate are disclosed. In one aspect, linking molecules are disclosed which can be used to increase the number of intra-complex binding interactions. Covalent bonds can be introduced to further increase the strength of these binding interactions. Inter-complex cross-linking can be utilized in connection with these methods to further strengthen and stabilize the disclosed binding complexes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.