Apoptosis signal-regulating kinase inhibitors
US9169243B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Dec 15, 2014 |
| Grant date | Oct 27, 2015 |
| Priority date | — |
| Expiry date | Dec 15, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application relates to compounds having the inhibitory activity to apoptosis signal-regulating kinase (ASK1), thus are thus useful in treating ASK1-mediated conditions, including autoimmune disorders, inflammatory diseases, cardiovascular diseases, diabetes, diabetic nephropathy, cardio-renal diseases, including kidney disease, fibrotic diseases, respiratory diseases, COPD, idiopathic pulmonary fibrosis, acute lung injury, acute and chronic liver diseases, and neurodegenerative diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.