Patent · US Active

Fused heterocyclic compounds as ion channel modulators

US9193694B2 · kind B2 · utility

9Cited by
25References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 26, 2013
Grant dateNov 24, 2015
Priority date
Expiry dateFeb 10, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/05
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I:wherein Z1, Z2, Z3, Z4, X, Y, R2, R3 and R4 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.