Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof

US9206175B2 · kind B2 · utility

Assignee

• Genentech, Inc. · US

Inventors

• Joseph P. Lyssikatos · South San Francisco, US
• Lewis Gazzard · Belmont, US
• Emily Hanan · Redwood City, US
• Samuel Kintz · Boulder, US
• Hans Purkey · South San Francisco, US

Key dates

• Filing date: Oct 31, 2013
• Grant date: Dec 8, 2015
• Expiry date: Oct 31, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides novel compounds having the general formula:wherein X1 is N or N+O−, and one of X2, X3 and X4 is N or N+—O− and the remainder of X2, X3 and X4 is C. R2, R3, R4, R5, R6. A, B and Y are as described herein. Additionally compositions compounds of Formula I and methods of use are further described herein.