Ring-fused pyrimidines and triazines and use thereof for the treatment and/or prophylaxis of cardiovascular diseases

US9216978B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Markus Follmann
• Johannes-Peter Stasch · Wuppertal, DE
• Gorden Redlich · Bochum, DE
• Jens Ackerstaff · Mülheim an der Ruhr, DE
• Nils Griebenow · Milford, US
• Andreas Knorr · Erkrath, DE
• Frank Wunder · Wuppertal, DE
• Volkhart Min-Jian Li · Velbert, DE
• Walter Kroh · Wuppertal, DE
• Lars Bärfacker · Oberhausen, DE

Key dates

• Filing date: Jul 5, 2011
• Grant date: Dec 22, 2015
• Expiry date: Sep 17, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/107
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel fused pyrimidines and triazines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.