Patent · US Active

Phase changing formulations of nucleic acid payloads

US9217146B2 · kind B2 · utility

0Cited by

0References

20Claims

0Family size

Assignee

Dicerna Pharmaceuticals, Inc. · US

Inventors

Bob D. Brown · Littleton, US
Sujit Basu · Lexington, US

Key dates

Filing date	Dec 13, 2013
Grant date	Dec 22, 2015
Priority date	—
Expiry date	Dec 13, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/32
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is based, at least in part, upon discovery of a process for identifying phase changing peptides. Such phase changing peptides are capable of enhancing in vitro and in vivo delivery of oligonucleotides (e.g., dsRNAs) in lipidic, vesicular, micellar and/or naked oligonucleotide formulations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.