2-oxo-2,3-dihydro-indoles for the treatment of CNS disorders

US9221816B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Daniela Brunner · The Bronx, US
• Jessica Malberg · Dobbs Ferry, US
• Bavani Shankar · Tarrytown, US
• Sabine Kolczewski · Lörrach, DE
• Anja Limberg · Penzberg, DE
• Eric Prinssen · Guebwiller, FR
• Claus Riemer · Glückstadt, DE
• Theodor Stoll · Basel, CH

Key dates

• Filing date: Mar 11, 2015
• Grant date: Dec 29, 2015
• Expiry date: Mar 11, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is concerned with 2-oxo-2,3-dihydro-indoles of general formulawhereinis phenyl or a heteroaryl group, selected from pyridinyl, pyrimidinyl, imidazolyl, isoxazolyl or pyrazolyl;is phenyl or pyridinyl, wherein the N atom in the pyridinyl group may be on all free positions;