Compositions and methods for inhibiting cytochrome P450
US9233952B2 · kind B2 · utility
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4References
21Claims
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Key dates
| Filing date | Jul 9, 2013 |
| Grant date | Jan 12, 2016 |
| Priority date | — |
| Expiry date | Aug 4, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/048
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of inhibiting cytochrome P450 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome P450. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome P450 enzymes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.