Heterocyclic compounds as positive modulators of metabotropic glutamate receptor 2 (mGlu2 receptor)

US9242933B2 · kind B2 · utility

Assignee

• Abb Vie Deutschland Gmbh & Co. KG · DE

Inventors

• Hervé Geneste · Schifferstadt, DE
• Daryl Sauer · Pleasant Prairie, US
• Wilfried Braje · Ludwigshafen, DE
• Wilhelm Amberg · Ludwigshafen, DE
• Mario Mezler · Ludwigshafen, DE
• Margaretha Henrica Maria Bakker · Ludwigshafen, DE

Key dates

• Filing date: May 23, 2008
• Grant date: Jan 26, 2016
• Expiry date: Dec 11, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to heterocyclic compounds which are positive modulators of metabotropic glutamate receptor. The present invention also relates to the use of these compounds for preparing a pharmaceutical composition and to a method of treating a medical disorder, selected from neurological and psychiatric disorders associated with glutamate dysfunction.