Patent · US Active

In vitro capture and analysis of circulating tumor cells

US9250242B2 · kind B2 · utility

8Cited by

0References

23Claims

0Family size

Assignees

Roche Molecular Systems, Inc. · US
University of North Carolina · US

Inventors

George A. Martin · Berkeley, US
Steven A. Soper · Baton Rouge, US
Makgorzata Witek · Chapel Hill, US
Jen Jen Yeh · Chapel Hill, US

Key dates

Filing date	Nov 8, 2013
Grant date	Feb 2, 2016
Priority date	—
Expiry date	Nov 8, 2033

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/96466
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

This invention provides methods and compositions for capturing circulating tumor cells (CTCs) as well as various divergent CTC phenotypes using seprase-specific affinity reagents. Methods of analyzing CTCs and assessing their metastatic potential in vivo and in vitro are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.