Patent · US Active

Modulators of ATP-binding cassette transporters

US9254291B2 · kind B2 · utility

50Cited by

132References

11Claims

0Family size

Assignee

Vertex Pharmaceuticals Incorporated · US

Inventors

Adam Looker · Newton, US
Benjamin Littler · Carlsbad, US
Anusuya Choudhury · Nazareth, US
Cristian Harrison · Beverly, US
Ravikanth Veluri · Burlington, US
Michael P. Ryan · Brookline, US
Licong Jiang · San Diego, US
Eduard Luss-Lusis · Arlington, US

Key dates

Filing date	Nov 8, 2012
Grant date	Feb 9, 2016
Priority date	—
Expiry date	Mar 3, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D498/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.