Dihydroquinoline-2-one derivatives
US9260408B2 · kind B2 · utility
1Cited by
1References
43Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 13, 2012 |
| Grant date | Feb 16, 2016 |
| Priority date | — |
| Expiry date | Jul 12, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1804
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides novel compounds having the general formula (I)wherein R1, R2, R3, R4, R5, R6, R7, A1, A2 and A3 are as described herein, compositions including the compounds and methods of using the compounds. These compounds are useful for therapy or prophylaxis in a mammal, and in particular as aldosterone synthase (CYP11B2 or CYP11B1) inhibitors for the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.