Bicyclic sulfone compounds for inhibition of RORgamma activity and the treatment of disease
US9266827B2 · kind B2 · utility
22Cited by
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52Claims
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Key dates
| Filing date | May 3, 2013 |
| Grant date | Feb 23, 2016 |
| Priority date | — |
| Expiry date | May 3, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/42
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides bicyclic sulfone compounds, pharmaceutical compositions, methods of inhibiting RORy activity, reducing the amount of iL-17 in a subject, and treating immune disorders and inflammatory disorders using such bicyclic sulfone compounds. Another aspect of the invention provides a method of treating a subject suffering from a medical disorder. The method comprises administering to the subject a therapeutically effective amount of one or more bicyclic sulfone compounds described herein. In certain other embodiments, the disorder is rheumatoid arthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.