Synthesis of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione

US9266858B2 · kind B2 · utility

Assignee

• CELGENE CORPORATION · US

Inventors

• Alexander L. Ruchelman · Cream Ridge, US
• Benjamin M. Cohen · Cranford, US
• Anusuya Choudhury · Nazareth, US
• Matthew Michael Kreilein · Fryeburg, US
• William W. Leong · Westfield, US
• Hon-Wah Man · Princeton, US

Key dates

• Filing date: Jun 10, 2015
• Grant date: Feb 23, 2016
• Expiry date: Jun 10, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Provided herein are processes for the preparation of 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof; or a pharmaceutically acceptable salt thereof.