Naphthalene acetic acid derivatives against HIV infection

US9284323B2 · kind B2 · utility

Assignee

• Gilead Sciences, Inc. · US

Inventors

• Kerim Babaoglu · Lansdale, US
• Gediminas Brizgys · Redwood City, US
• Hongyan Guo · San Mateo, US
• Paul Hrvatin · South San Francisco, US
• Eric Lansdon · San Jose, US
• John O. Link · San Francisco, US
• Hongtao Liu · Cupertino, US
• Ryan McFadden · Foster City, US
• Michael L. Mitchell · Union City, US
• Yingmei Qi · Foster City, US
• Paul A. Roethle · San Francisco, US
• Randall W. Vivian · San Mateo, US
• Lianhong Xu · Durham, US
• Hong Yang · Foster City, US

Key dates

• Filing date: Jan 3, 2013
• Grant date: Mar 15, 2016
• Expiry date: Jan 3, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides compounds and salts thereof as d herein. The invention also provides pharmaceutical compositions comprising a compound disclosed herein, processes for preparing compounds disclosed herein, intermediates useful for preparing compounds disclosed herein and therapeutic methods for treating an HIV infection, treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds disclosed herein.