Method of preparing lipid nanoparticles
US9302241B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Dec 11, 2009 |
| Grant date | Apr 5, 2016 |
| Priority date | — |
| Expiry date | Jun 25, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a method for preparing nanocapsules having a liquid lipid core and a solid shell and charged in their lipid core with at least one hydrophilic active agent involving combining microemulsions where the active agent remains in the hydrophilic phase of a first microemulsion and chill-hardening the mixture to obtain the nanocapsules charged with the hydrophilic active agent. The nanocapsules comprise the lipid core which is liquid at room temperature and the nanocapsules are encapsulated in a film which is solid at room temperature.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.