N-[3-(2-carboxyethyl)phenyl]piperidin-1-ylacetamide derivatives and use thereof as activators of soluble guanylate cyclase

US9309198B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Thomas Lampe · Mülheim an der Ruhr, DE
• Michael Hahn · Langenfeld, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Karl-Heinz Schlemmer · Wuppertal, DE
• Frank Wunder · Wuppertal, DE
• Sherif El Sheikh · Essen, DE
• Volkhart Min-Jian Li · Velbert, DE
• Eva Maria Becker-Pelster · Wuppertal, DE
• Friederike Stoll · Mülheim an der Ruhr, DE
• Andreas Knorr · Erkrath, DE

Key dates

• Filing date: May 17, 2013
• Grant date: Apr 12, 2016
• Expiry date: May 17, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/15
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel substituted 2-(piperidin-1-yl)acetamide derivatives, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of cardiovascular diseases.