Process for making hydroxylated cyclopentylpyrimidine compounds
US9309204B2 · kind B2 · utility
7Cited by
3References
16Claims
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Key dates
| Filing date | May 17, 2013 |
| Grant date | Apr 12, 2016 |
| Priority date | — |
| Expiry date | May 17, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides new processes for making and purifying hydroxylated cyclopenta[d]pyrimidine compounds, which are useful for the treatment of diseases such as cancer as AKT protein kinase inhibitors, including the compound (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.