Phage displaying system expressing single chain antibody
US9309522B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | May 20, 2013 |
| Grant date | Apr 12, 2016 |
| Priority date | — |
| Expiry date | May 22, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/00022
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are nucleic acid libraries for identifying a signal peptide that facilitates production of disulfide-stabilized single chain antibody, and for facilitating production of a disulfide-stabilized single chain antibody. Also disclosed are host cell libraries and phage libraries including the nucleic acid libraries. Further disclosed are methods for identifying a signal peptide that facilitates production of disulfide-stabilized single chain antibody, and methods for producing a disulfide-stabilized single chain antibody and non-fusion form thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.