Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof
US9322018B2 · kind B2 · utility
27Cited by
1References
41Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 18, 2013 |
| Grant date | Apr 26, 2016 |
| Priority date | — |
| Expiry date | Dec 18, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/3515
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ANGPTL3 gene, as well as methods of inhibiting expression of ANGPTL3 and methods of treating subjects having a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia, using such dsRNA compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.